Tuesday, December 14, 2021
| Time | Event | Venue/Details |
|---|---|---|
| 6:00pm | Boys Basketball - Woodland Hills vs Penn-Trafford | |
| 6:00pm | Girls Basketball - Moon @ Montour | |
| 6:00pm | Girls Basketball - Trinity @ Washington | |
| 7:00pm | Boys Basketball - Fox Chapel vs Shaler | |
| 7:00pm | Boys Basketball - Connellsville @ Mt. Pleasant | |
| 7:00pm | Boys Basketball - McKeesport vs South Allegheny | |
| 7:00pm | Boys Basketball - Hampton @ Knoch | |
| 7:00pm | Boys Basketball - Plum @ Brashear | |
| 7:00pm | Girls Basketball - Shaler @ Fox Chapel | |
| 7:00pm | Girls Basketball - Laurel Highlands @ Brownsville | |
| 7:30pm | Boys Basketball - Butler @ North Hills # | |
| 7:30pm | Boys Basketball - North Allegheny @ Seneca Valley # | |
| 7:30pm | Boys Basketball - Pine-Richland vs Mt. Lebanon | |
| 7:30pm | Boys Basketball - Bethel Park @ Hempfield | |
| 7:30pm | Boys Basketball - Canon-McMillan @ Latrobe | |
| 7:30pm | Boys Basketball - Peters Township vs Norwin | |
| 7:30pm | Boys Basketball - Greensburg Salem @ Derry | |
| 7:30pm | Boys Basketball - Albert Gallatin vs Uniontown | |
| 7:30pm | Boys Basketball - West Mifflin @ Serra Catholic | |
| 7:30pm | Boys Basketball - Moon @ Fort Cherry | |
| 7:30pm | Boys Basketball - Trinity @ Washington | |
| 7:30pm | Boys Basketball - Chartiers Valley @ Quaker Valley | |
| 7:30pm | Boys Basketball - West Allegheny vs Hopewell | |
| 7:30pm | Boys Basketball - South Fayette @ Montour | |
| 7:30pm | Boys Basketball - Kiski Area @ Armstrong | |
| 7:30pm | Boys Basketball - Penn Hills @ Allderdice | |
| 7:30pm | Boys Basketball - Indiana vs Punxsutawney | |
| 7:30pm | Girls Basketball - Norwin vs Upper St. Clair | |
| 7:30pm | Girls Basketball - South Fayette @ Thomas Jefferson | |
| 7:30pm | Girls Basketball - Plum @ Penn Hills | |
| 7:30pm | Boys Basketball - Franklin Regional vs Baldwin |
# denotes a conference game