Monday, December 13, 2021
| Time | Event | Venue/Details |
|---|---|---|
| 6:00pm | Boys Basketball - Woodland Hills vs Baldwin | |
| 7:00pm | Boys Basketball - McKeesport vs Propel Braddock Hills | |
| 7:30pm | Boys Basketball - Penn-Trafford @ Franklin Regional | |
| 7:30pm | Boys Basketball - Thomas Jefferson vs Uniontown | |
| 7:30pm | Boys Basketball - Moon vs Ambridge | |
| 7:30pm | Boys Basketball - Armstrong vs River Valley | |
| 7:30pm | Boys Basketball - Highlands vs Imani Christian | |
| 7:30pm | Girls Basketball - Butler vs Franklin Regional | |
| 7:30pm | Girls Basketball - North Hills vs Highlands | |
| 7:30pm | Girls Basketball - Pine-Richland @ Hempfield | |
| 7:30pm | Girls Basketball - Seneca Valley vs New Castle | |
| 7:30pm | Girls Basketball - Canon-McMillan @ Upper St. Clair # | |
| 7:30pm | Girls Basketball - Mt. Lebanon vs Altoona | |
| 7:30pm | Girls Basketball - Peters Township vs Oakland Catholic | |
| 7:30pm | Girls Basketball - Chartiers Valley @ Winchester Thurston | |
| 7:30pm | Girls Basketball - West Allegheny vs Hopewell | |
| 7:30pm | Girls Basketball - Moon @ Quaker Valley | |
| 7:30pm | Girls Basketball - Lincoln Park @ Beaver Falls | |
| 7:30pm | Girls Basketball - Armstrong @ Gateway | |
| 7:30pm | Girls Basketball - Hampton vs Knoch | |
| 7:30pm | Girls Basketball - Mars @ Allderdice | |
| 7:30pm | Girls Basketball - Laurel Highlands vs Belle Vernon | |
| 7:30pm | Girls Basketball - Ringgold vs Washington | |
| 7:30pm | Girls Basketball - Thomas Jefferson @ Southmoreland | |
| 7:30pm | Girls Basketball - Uniontown vs Frazier | |
| 7:30pm | Girls Basketball - Greensburg Salem @ Connellsville |
# denotes a conference game