Thursday, May 5, 2022
| Time | Event | Venue/Details |
|---|---|---|
| 3:45pm | Softball - Pine-Richland @ Fox Chapel | |
| 3:45pm | Softball - Fox Chapel vs Mars # | |
| 3:45pm | Softball - Shaler @ Oakland Catholic # | |
| 4:00pm | Baseball - Seneca Valley vs Norwin | |
| 4:00pm | Baseball - Franklin Regional vs Plum | |
| 4:00pm | Baseball - Fox Chapel @ Bethel Park | |
| 4:00pm | Baseball - Hampton vs North Hills | |
| 4:00pm | Baseball - West Allegheny @ New Castle | |
| 4:00pm | Baseball - West Allegheny vs Hopewell | |
| 4:00pm | Softball - Bethel Park @ Hampton | |
| 4:00pm | Softball - North Allegheny @ North Hills | |
| 4:00pm | Softball - Penn-Trafford @ Greensburg Salem | |
| 4:00pm | Softball - Oakland Catholic @ Bishop Canevin | |
| 4:15pm | Softball - Mt. Lebanon vs Trinity | |
| 4:30pm | Baseball - North Allegheny @ Mars | |
| 4:30pm | Baseball - Bethel Park @ Thomas Jefferson # | |
| 4:30pm | Softball - Moon vs South Fayette # | |
| 4:45pm | Baseball - Central Catholic vs Baldwin | |
| 4:45pm | Baseball - Armstrong vs Highlands | |
| 4:45pm | Softball - Armstrong vs Hempfield | |
| 5:00pm | Baseball - Pine-Richland @ North Catholic | |
| 5:00pm | Baseball - Hempfield @ Laurel Highlands | |
| 5:00pm | Baseball - Hampton vs Plum # | |
| 5:00pm | Baseball - Connellsville @ Mt. Pleasant | |
| 5:00pm | Softball - Butler vs Knoch | |
| 5:00pm | Softball - Franklin Regional vs Kiski Area # | |
| 5:15pm | Baseball - Canon-McMillan @ Moon | |
| 5:15pm | Baseball - Trinity @ Quaker Valley | |
| 5:15pm | Softball - Canon-McMillan vs Mt. Lebanon # | |
| 5:30pm | Baseball - Penn-Trafford vs Yough | |
| 6:15pm | Softball - Plum @ Our Lady of Sacred Heart | |
| 7:00pm | Baseball - Peters Township vs Ringgold | |
| 7:00pm | Baseball - Fox Chapel @ South Park | |
| 8:00pm | Baseball - North Allegheny vs Shaler | |
| 8:00pm | Baseball - Chartiers Valley @ Montour | |
| 8:00pm | Softball - Baldwin @ Upper St. Clair | |
| 8:00pm | Baseball - Upper St. Clair vs West Mifflin |
# denotes a conference game