Friday, May 6, 2022
| Time | Event | Venue/Details |
|---|---|---|
| 12:30pm | Baseball - Latrobe vs Mifflin County | |
| 3:45pm | Softball - Baldwin @ Keystone Oaks | |
| 3:45pm | Softball - Fox Chapel vs Burrell | |
| 4:00pm | Baseball - Gateway @ Penn Hills | |
| 4:00pm | Baseball - McKeesport @ Woodland Hills | |
| 4:00pm | Softball - Canon-McMillan @ Albert Gallatin | |
| 4:00pm | Softball - Indiana vs Cambria Heights | |
| 4:00pm | Softball - Shaler @ Deer Lakes | |
| 4:15pm | Baseball - Albert Gallatin vs Northern Garrett (MD) | |
| 4:15pm | Softball - Thomas Jefferson @ Elizabeth Forward | |
| 5:00pm | Softball - Peters Township @ Penn Hills | |
| 7:00pm | Baseball - North Allegheny vs Hempfield | |
| 7:00pm | Softball - Bethel Park @ Chartiers Valley |
# denotes a conference game