Thursday, December 16, 2021
| Time | Event | Venue/Details |
|---|---|---|
| 1:30pm | Girls Basketball - Greensburg Salem vs South Park | |
| 7:00pm | Girls Basketball - Canon-McMillan vs West Allegheny | |
| 7:00pm | Girls Basketball - Fox Chapel vs Indiana # | |
| 7:30pm | Boys Basketball - Greensburg Salem @ Laurel Highlands | |
| 7:30pm | Boys Basketball - Albert Gallatin @ Waynesburg | |
| 7:30pm | Boys Basketball - West Mifflin vs Carrick | |
| 7:30pm | Boys Basketball - Trinity vs Brownsville | |
| 7:30pm | Boys Basketball - Chartiers Valley vs Bishop Canevin | |
| 7:30pm | Boys Basketball - Shaler @ New Castle | |
| 7:30pm | Girls Basketball - Norwin vs Shaler # | |
| 7:30pm | Girls Basketball - Penn-Trafford @ Seneca Valley # | |
| 7:30pm | Girls Basketball - Bethel Park @ Hempfield # | |
| 7:30pm | Girls Basketball - Peters Township @ Baldwin # | |
| 7:30pm | Girls Basketball - Upper St. Clair @ South Fayette | |
| 7:30pm | Girls Basketball - Plum @ Hampton # | |
| 7:30pm | Girls Basketball - Armstrong vs Mars # | |
| 7:30pm | Girls Basketball - Albert Gallatin vs Laurel Highlands # | |
| 7:30pm | Girls Basketball - Connellsville vs Thomas Jefferson # |
# denotes a conference game