Tuesday, January 11, 2022
| Time | Event | Venue/Details |
|---|---|---|
| 5:30pm | Boys Basketball - Latrobe @ McKeesport # | |
| 7:00pm | Boys Basketball - Fox Chapel vs Penn-Trafford # | |
| 7:00pm | Girls Basketball - Fox Chapel vs Hampton # | |
| 7:00pm | Girls Basketball - Latrobe @ McKeesport # | |
| 7:30pm | Boys Basketball - Butler vs North Hills # | |
| 7:30pm | Boys Basketball - North Allegheny vs Seneca Valley # | |
| 7:30pm | Boys Basketball - Pine-Richland vs Franklin Regional | |
| 7:30pm | Boys Basketball - Bethel Park vs Upper St. Clair # | |
| 7:30pm | Boys Basketball - Canon-McMillan @ Baldwin # | |
| 7:30pm | Boys Basketball - Mt. Lebanon @ Peters Township # | |
| 7:30pm | Boys Basketball - Hempfield @ Central Catholic # | |
| 7:30pm | Boys Basketball - Norwin @ Greensburg Salem # | |
| 7:30pm | Boys Basketball - Albert Gallatin vs Laurel Highlands # | |
| 7:30pm | Boys Basketball - Connellsville vs Thomas Jefferson # | |
| 7:30pm | Boys Basketball - Ringgold vs West Mifflin # | |
| 7:30pm | Boys Basketball - Moon vs South Fayette # | |
| 7:30pm | Boys Basketball - Trinity @ New Castle # | |
| 7:30pm | Boys Basketball - Chartiers Valley @ West Allegheny # | |
| 7:30pm | Boys Basketball - Gateway vs Penn Hills # | |
| 7:30pm | Boys Basketball - Kiski Area vs Woodland Hills # | |
| 7:30pm | Boys Basketball - Hampton @ Shaler # | |
| 7:30pm | Boys Basketball - Plum @ Mars # | |
| 7:30pm | Boys Basketball - Highlands @ Indiana # | |
| 7:30pm | Girls Basketball - Connellsville @ Trinity # | |
| 7:30pm | Girls Basketball - Franklin Regional vs Greensburg Salem # | |
| 7:30pm | Girls Basketball - Gateway vs Penn Hills # |
# denotes a conference game