Friday, January 15, 2021
| Time | Event | Venue/Details |
|---|---|---|
| 5:00pm | Girls Basketball - Chartiers Valley @ Moon # | |
| 6:00pm | Girls Basketball - Mt. Lebanon @ Woodland Hills | |
| 6:00pm | Girls Basketball - Latrobe @ Gateway # | |
| 7:00pm | Boys Basketball - Trinity vs West Allegheny # | |
| 7:00pm | Boys Basketball - Franklin Regional @ McKeesport # | |
| 7:30pm | Boys Basketball - Woodland Hills vs Berlin Brothersvalley | |
| 7:30pm | Boys Basketball - North Allegheny vs Pine-Richland # | |
| 7:30pm | Boys Basketball - Seneca Valley @ Butler # | |
| 7:30pm | Boys Basketball - Peters Township vs Baldwin # | |
| 7:30pm | Boys Basketball - Upper St. Clair vs Canon-McMillan # | |
| 7:30pm | Boys Basketball - Fox Chapel @ Norwin # | |
| 7:30pm | Boys Basketball - Hempfield @ Penn-Trafford # | |
| 7:30pm | Boys Basketball - Albert Gallatin @ Connellsville # | |
| 7:30pm | Boys Basketball - Laurel Highlands @ West Mifflin # | |
| 7:30pm | Boys Basketball - Gateway vs Latrobe # | |
| 7:30pm | Boys Basketball - Penn Hills @ Kiski Area # | |
| 7:30pm | Boys Basketball - Shaler vs Armstrong # | |
| 7:30pm | Boys Basketball - Hampton @ Indiana # | |
| 7:30pm | Boys Basketball - Highlands @ Mars # | |
| 7:30pm | Boys Basketball - Thomas Jefferson @ Bethel Park | |
| 7:30pm | Girls Basketball - Connellsville @ Uniontown # | |
| 7:30pm | Girls Basketball - Hampton vs Peters Township # | |
| 7:30pm | Girls Basketball - Thomas Jefferson vs Southmoreland | |
| 8:00pm | Boys Basketball - Chartiers Valley @ Moon # |
# denotes a conference game