Friday, September 23, 2022
| Time | Event | Venue/Details |
|---|---|---|
| 8:00pm | Football - Canon-McMillan @ South Fayette | |
| 8:00pm | Football - Central Catholic vs North Allegheny # | |
| 8:00pm | Football - Seneca Valley @ Mt. Lebanon # | |
| 8:00pm | Football - Peters Township @ Upper St. Clair # | |
| 8:00pm | Football - Gateway vs Plum # | |
| 8:00pm | Football - Penn-Trafford @ Hempfield # | |
| 8:00pm | Football - Fox Chapel vs Pine-Richland # | |
| 8:00pm | Football - Baldwin vs Bethel Park # | |
| 8:00pm | Football - Moon @ Mars | |
| 8:00pm | Football - Norwin vs Woodland Hills | |
| 8:00pm | Football - North Hills @ Penn Hills # | |
| 9:30pm | Girls Soccer - North Allegheny @ Seneca Valley # |
# denotes a conference game