Monday, April 19, 2021
| Time | Event | Venue/Details |
|---|---|---|
| 4:30pm | Baseball - North Allegheny @ Central Catholic # | |
| 4:30pm | Baseball - Seneca Valley @ Allderdice # | |
| 4:45pm | Baseball - Hampton vs Fox Chapel # | |
| 4:45pm | Baseball - Mars vs Central Valley | |
| 4:45pm | Softball - North Hills @ Oakland Catholic # | |
| 4:45pm | Softball - South Fayette vs Montour | |
| 4:45pm | Softball - Penn Hills vs St. Joseph | |
| 5:00pm | Baseball - Butler @ Pine-Richland # | |
| 5:00pm | Baseball - Norwin vs Canon-McMillan # | |
| 5:00pm | Baseball - Hempfield vs Mt. Lebanon # | |
| 5:00pm | Baseball - Franklin Regional @ McKeesport # | |
| 5:00pm | Baseball - Penn-Trafford vs Kiski Area # | |
| 5:00pm | Baseball - Armstrong @ Penn Hills # | |
| 5:00pm | Baseball - South Fayette @ Shaler # | |
| 5:00pm | Baseball - Bethel Park vs Peters Township # | |
| 5:00pm | Softball - Shaler vs Mars # | |
| 5:00pm | Softball - Moon @ Western Beaver # | |
| 5:00pm | Softball - Butler vs Highlands | |
| 5:00pm | Softball - Thomas Jefferson vs West Mifflin | |
| 5:15pm | Baseball - West Allegheny vs Chartiers Valley # | |
| 5:15pm | Baseball - North Hills vs Moon # | |
| 5:15pm | Softball - Mt. Lebanon vs Hampton | |
| 5:30pm | Baseball - Plum @ Keystone Oaks | |
| 8:00pm | Baseball - Baldwin @ Upper St. Clair # | |
| 8:00pm | Baseball - Gateway @ Latrobe # |
# denotes a conference game