Wednesday, October 13, 2021
| Time | Event | Venue/Details |
|---|---|---|
| 7:00pm | Boys Soccer - Allderdice @ Central Catholic # | |
| 7:00pm | Girls Volleyball - Hempfield vs Oakland Catholic # | |
| 7:30pm | Boys Soccer - Butler vs Seneca Valley # | |
| 7:30pm | Boys Soccer - Fox Chapel @ Pine-Richland # | |
| 7:30pm | Boys Soccer - North Allegheny vs North Hills # | |
| 7:30pm | Boys Soccer - Norwin @ Penn-Trafford # | |
| 7:30pm | Girls Soccer - Baldwin vs Bethel Park # | |
| 8:00pm | Girls Soccer - Canon-McMillan vs Peters Township # | |
| 8:00pm | Girls Soccer - Mt. Lebanon @ Upper St. Clair # | |
| 8:30pm | Boys Soccer - Hempfield vs Latrobe # |
# denotes a conference game