Thursday, February 18, 2021
| Time | Event | Venue/Details |
|---|---|---|
| 4:00pm | Girls Basketball - Norwin vs Pine-Richland # | |
| 4:15pm | Boys Basketball - Fox Chapel vs Greensburg Salem # | |
| 6:00pm | Girls Basketball - Fox Chapel vs Indiana # | |
| 7:00pm | Girls Basketball - South Fayette @ West Allegheny # | |
| 7:00pm | Girls Basketball - McKeesport vs Hempfield | |
| 7:30pm | Boys Basketball - Franklin Regional @ Kiski Area # | |
| 7:30pm | Boys Basketball - Upper St. Clair vs Gateway | |
| 7:30pm | Girls Basketball - Mt. Lebanon vs Baldwin # | |
| 7:30pm | Girls Basketball - Upper St. Clair @ Bethel Park # | |
| 7:30pm | Girls Basketball - Oakland Catholic @ Moon # | |
| 7:30pm | Girls Basketball - Mars vs Armstrong # | |
| 7:30pm | Girls Basketball - Hampton vs Kiski Area # | |
| 7:30pm | Girls Basketball - Albert Gallatin @ Ringgold # | |
| 7:30pm | Girls Basketball - Woodland Hills vs Latrobe # | |
| 7:30pm | Girls Basketball - Gateway vs Freeport | |
| 7:30pm | Girls Basketball - Lincoln Park @ St. Joseph |
# denotes a conference game