Friday, October 25, 2019
| Time | Event | Venue/Details |
|---|---|---|
| 7:00pm | Football - Canon-McMillan vs Butler # | |
| 7:00pm | Football - Hempfield vs Plum | |
| 7:00pm | Football - North Allegheny @ Pine-Richland # | |
| 7:00pm | Football - Peters Township @ Baldwin # | |
| 7:00pm | Football - West Allegheny vs Moon # | |
| 7:00pm | Football - Woodland Hills @ Chartiers Valley # | |
| 7:00pm | Football - Connellsville vs Albert Gallatin | |
| 7:00pm | Football - Franklin Regional vs Penn-Trafford # | |
| 7:00pm | Football - Gateway @ McKeesport # | |
| 7:00pm | Football - Latrobe vs Highlands | |
| 7:00pm | Football - Armstrong @ Kiski Area # | |
| 7:00pm | Football - Fox Chapel vs Shaler # | |
| 7:00pm | Football - Hampton vs Mars # | |
| 7:00pm | Football - North Hills @ Penn Hills # | |
| 7:30pm | Football - Mt. Lebanon vs Central Catholic # | |
| 7:30pm | Football - Seneca Valley vs Norwin # | |
| 7:30pm | Football - Bethel Park @ Upper St. Clair # |
# denotes a conference game