Tuesday, January 4, 2022
| Time | Event | Venue/Details |
|---|---|---|
| 5:30pm | Girls Basketball - McKeesport vs Woodland Hills # | |
| 6:00pm | Girls Basketball - Franklin Regional vs Penn Hills # | |
| 7:00pm | Boys Basketball - McKeesport vs Woodland Hills # | |
| 7:00pm | Girls Basketball - Latrobe vs River Valley | |
| 7:30pm | Boys Basketball - Butler vs North Allegheny # | |
| 7:30pm | Boys Basketball - North Hills vs Pine-Richland # | |
| 7:30pm | Boys Basketball - Bethel Park @ Peters Township # | |
| 7:30pm | Boys Basketball - Canon-McMillan vs Mt. Lebanon # | |
| 7:30pm | Boys Basketball - Upper St. Clair @ Baldwin # | |
| 7:30pm | Boys Basketball - Fox Chapel @ Greensburg Salem # | |
| 7:30pm | Boys Basketball - Hempfield vs Norwin # | |
| 7:30pm | Boys Basketball - Penn-Trafford @ Central Catholic # | |
| 7:30pm | Boys Basketball - Albert Gallatin vs West Mifflin # | |
| 7:30pm | Boys Basketball - Connellsville vs Ringgold # | |
| 7:30pm | Boys Basketball - Laurel Highlands vs Thomas Jefferson # | |
| 7:30pm | Boys Basketball - Moon vs New Castle # | |
| 7:30pm | Boys Basketball - West Allegheny vs South Fayette # | |
| 7:30pm | Boys Basketball - Franklin Regional vs Penn Hills # | |
| 7:30pm | Boys Basketball - Plum @ Shaler # | |
| 7:30pm | Boys Basketball - Armstrong vs Highlands # | |
| 7:30pm | Boys Basketball - Mars @ Indiana # | |
| 7:30pm | Girls Basketball - Greensburg Salem @ Southmoreland |
# denotes a conference game