Monday, December 20, 2021
| Time | Event | Venue/Details |
|---|---|---|
| 6:00pm | Boys Basketball - Peters Township vs Hempfield | |
| 7:00pm | Boys Basketball - Albert Gallatin @ Brownsville | |
| 7:30pm | Boys Basketball - Canon-McMillan vs Nazareth Prep | |
| 7:30pm | Boys Basketball - Upper St. Clair vs Winchester Thurston | |
| 7:30pm | Boys Basketball - Thomas Jefferson @ Trinity | |
| 7:30pm | Boys Basketball - Chartiers Valley vs Central Catholic | |
| 7:30pm | Boys Basketball - West Allegheny vs Perry | |
| 7:30pm | Girls Basketball - Butler @ Shaler # | |
| 7:30pm | Girls Basketball - North Allegheny @ Penn-Trafford # | |
| 7:30pm | Girls Basketball - North Hills vs Seneca Valley # | |
| 7:30pm | Girls Basketball - Norwin @ Pine-Richland # | |
| 7:30pm | Girls Basketball - Bethel Park vs McKeesport | |
| 7:30pm | Girls Basketball - Canon-McMillan @ Mt. Lebanon # | |
| 7:30pm | Girls Basketball - Hempfield @ Peters Township # | |
| 7:30pm | Girls Basketball - Moon vs Indiana | |
| 7:30pm | Girls Basketball - South Fayette vs Gateway | |
| 7:30pm | Girls Basketball - Lincoln Park vs St. Joseph's | |
| 7:30pm | Girls Basketball - Fox Chapel @ Mars # | |
| 7:30pm | Girls Basketball - Albert Gallatin @ Thomas Jefferson # | |
| 7:30pm | Girls Basketball - Connellsville @ Ringgold # | |
| 7:30pm | Girls Basketball - Franklin Regional @ Woodland Hills # | |
| 8:00pm | Girls Basketball - West Allegheny @ Carlynton |
# denotes a conference game