Monday, April 5, 2021
| Time | Event | Venue/Details |
|---|---|---|
| 4:45pm | Softball - Shaler @ Armstrong | |
| 4:45pm | Softball - Hampton vs Upper St. Clair | |
| 5:00pm | Softball - North Hills vs Chartiers Valley | |
| 5:00pm | Softball - Penn-Trafford vs Norwin | |
| 5:15pm | Softball - Mt. Lebanon vs South Park | |
| 5:30pm | Softball - Indiana @ Punxsutawney |
# denotes a conference game