Tuesday, February 23, 2021
| Time | Event | Venue/Details |
|---|---|---|
| 4:00pm | Girls Basketball - Connellsville vs Ringgold # | |
| 6:00pm | Girls Basketball - Woodland Hills @ McKeesport # | |
| 6:00pm | Girls Basketball - Greensburg Salem @ Monessen | |
| 6:30pm | Girls Basketball - Baldwin vs Peters Township # | |
| 7:00pm | Boys Basketball - Penn Hills vs Woodland Hills # | |
| 7:30pm | Boys Basketball - Bethel Park vs Canon-McMillan # | |
| 7:30pm | Boys Basketball - Gateway @ Kiski Area # | |
| 7:30pm | Boys Basketball - Moon vs Avonworth | |
| 7:30pm | Boys Basketball - Central Catholic @ Baldwin | |
| 7:30pm | Boys Basketball - Chartiers Valley @ Peters Township | |
| 7:30pm | Boys Basketball - Mt. Lebanon vs North Catholic | |
| 7:30pm | Boys Basketball - Ringgold @ Serra Catholic | |
| 7:30pm | Boys Basketball - Fox Chapel vs Shady Side Academy | |
| 7:30pm | Boys Basketball - South Fayette @ Aliquippa | |
| 7:30pm | Boys Basketball - Thomas Jefferson vs Trinity | |
| 7:30pm | Girls Basketball - Mars vs Indiana # | |
| 7:30pm | Girls Basketball - Thomas Jefferson @ Uniontown # | |
| 7:30pm | Girls Basketball - Fox Chapel @ Brentwood | |
| 7:30pm | Girls Basketball - Latrobe @ Albert Gallatin | |
| 7:30pm | Girls Basketball - South Fayette vs Southmoreland |
# denotes a conference game