Friday, September 21, 2018
| Time | Event | Venue/Details |
|---|---|---|
| 3:30pm | Girls Soccer - Seneca Valley vs Mars | |
| 3:30pm | Girls Soccer - Hempfield @ Plum | |
| 6:30pm | Football - Kiski Area @ Penn Hills # | |
| 7:00pm | Football - Hempfield @ Canon-McMillan # | |
| 7:00pm | Football - Pine-Richland @ Norwin # | |
| 7:00pm | Football - Baldwin @ Woodland Hills # | |
| 7:00pm | Football - Moon @ Chartiers Valley # | |
| 7:00pm | Football - Upper St. Clair vs West Allegheny # | |
| 7:00pm | Football - Albert Gallatin @ Penn-Trafford # | |
| 7:00pm | Football - Connellsville @ Latrobe # | |
| 7:00pm | Football - Franklin Regional vs Shaler | |
| 7:00pm | Football - Gateway @ Ringgold | |
| 7:00pm | Football - Armstrong @ Mars # | |
| 7:00pm | Football - Fox Chapel vs Hampton # | |
| 7:30pm | Football - Central Catholic @ Bethel Park | |
| 7:30pm | Football - North Allegheny @ Mt. Lebanon # | |
| 7:30pm | Football - Peters Township @ North Hills | |
| 7:30pm | Football - Butler vs Seneca Valley # |
# denotes a conference game