Monday, May 21, 2018
| Time | Event | Venue/Details |
|---|---|---|
| 4:00pm | Softball - Albert Gallatin vs Kiski Area | |
| 4:00pm | Softball - Latrobe vs Peters Township | |
| 5:00pm | Softball - Franklin Regional vs Connellsville | |
| 5:00pm | Softball - Penn-Trafford vs Thomas Jefferson | |
| 5:00pm | Softball - North Allegheny vs Norwin | |
| 6:00pm | Softball - West Allegheny vs Trinity | |
| 6:00pm | Softball - Baldwin vs Mt. Lebanon | |
| 7:00pm | Softball - Hempfield vs Canon-McMillan |
# denotes a conference game