Friday, October 7, 2016
| Time | Event | Venue/Details |
|---|---|---|
| 5:30pm | Girls Soccer - North Allegheny vs Altoona | |
| 7:00pm | Football - North Allegheny @ Penn Hills # | |
| 7:00pm | Football - Altoona @ Hempfield # | |
| 7:00pm | Football - Mt. Lebanon @ Norwin # | |
| 7:00pm | Football - Baldwin @ Connellsville | |
| 7:00pm | Football - Chartiers Valley @ Moon # | |
| 7:00pm | Football - Fox Chapel @ Hampton # | |
| 7:00pm | Football - Armstrong vs Latrobe # | |
| 7:00pm | Football - Gateway vs Plum # | |
| 7:00pm | Football - Kiski Area @ McKeesport # | |
| 7:30pm | Football - Butler vs Central Catholic # | |
| 7:30pm | Football - Pine-Richland @ Peters Township | |
| 7:30pm | Football - Seneca Valley @ Bethel Park | |
| 7:30pm | Football - North Hills vs Woodland Hills # | |
| 7:30pm | Football - Upper St. Clair vs West Allegheny # | |
| 7:30pm | Football - Franklin Regional @ Penn-Trafford # | |
| 7:30pm | Boys Soccer - Shaler vs Allderdice |
# denotes a conference game