Friday, September 9, 2016
| Time | Event | Venue/Details |
|---|---|---|
| 7:00pm | Football - Butler @ Altoona | |
| 7:00pm | Football - Penn Hills @ Canon-McMillan | |
| 7:00pm | Football - Shaler @ Norwin | |
| 7:00pm | Football - Hempfield vs Mt. Lebanon # | |
| 7:00pm | Football - Baldwin @ Hampton # | |
| 7:00pm | Football - Chartiers Valley vs Latrobe | |
| 7:00pm | Football - Fox Chapel vs Woodland Hills # | |
| 7:00pm | Football - Armstrong @ McKeesport # | |
| 7:00pm | Football - Connellsville @ Gateway # | |
| 7:00pm | Football - Franklin Regional vs Kiski Area # | |
| 7:00pm | Football - Penn-Trafford @ Plum # | |
| 7:30pm | Football - Central Catholic vs North Allegheny # | |
| 7:30pm | Football - Pine-Richland vs Seneca Valley # | |
| 7:30pm | Football - Bethel Park vs Peters Township # | |
| 7:30pm | Football - Moon @ Upper St. Clair # | |
| 7:30pm | Football - North Hills vs West Allegheny # |
# denotes a conference game